Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 10/100mg | ||||
360 pill | 10/100mg | NZD428.05 | NZD1.19 | |
180 pill | 10/100mg | NZD237.80 | NZD1.32 | |
120 pill | 10/100mg | NZD180.04 | NZD1.49 | |
90 pill | 10/100mg | NZD149.47 | NZD1.66 | |
60 pill | 10/100mg | NZD113.79 | NZD1.90 | |
30 pill | 10/100mg | NZD67.93 | NZD2.28 | |
Dosage: 25/100mg | ||||
360 pill | 25/100mg | NZD501.09 | NZD1.39 | |
180 pill | 25/100mg | NZD283.66 | NZD1.58 | |
120 pill | 25/100mg | NZD215.71 | NZD1.80 | |
90 pill | 25/100mg | NZD178.34 | NZD1.99 | |
60 pill | 25/100mg | NZD137.58 | NZD2.29 | |
30 pill | 25/100mg | NZD84.92 | NZD2.80 | |
Dosage: 25/250mg | ||||
360 pill | 25/250mg | NZD580.93 | NZD1.61 | |
180 pill | 25/250mg | NZD329.52 | NZD1.83 | |
120 pill | 25/250mg | NZD258.18 | NZD2.16 | |
90 pill | 25/250mg | NZD214.02 | NZD2.38 | |
60 pill | 25/250mg | NZD157.96 | NZD2.63 | |
30 pill | 25/250mg | NZD90.01 | NZD2.97 |

Carbidopa / Levodopa Description
Overview of Carbidopa / Levodopa
Carbidopa / Levodopa is a combination medication commonly prescribed to manage symptoms of Parkinson's disease. Parkinson's disease is a progressive nervous system disorder that affects movement, causing symptoms such as tremors, stiffness, and difficulty with coordination. This medication works by replenishing dopamine levels in the brain, which are typically low in individuals with Parkinson’s. The combination includes Levodopa, the precursor to dopamine, and Carbidopa, which prevents Levodopa from breaking down before reaching the brain. This synergy enhances the effectiveness of the medication and reduces some of the side effects associated with Levodopa alone.
How does Carbidopa / Levodopa work?
Levodopa crosses the blood-brain barrier and is converted into dopamine, helping to control motor symptoms. However, Levodopa can be broken down in the bloodstream before reaching the brain, which limits its effectiveness and causes side effects like nausea. Carbidopa inhibits an enzyme called DOPA decarboxylase outside of the brain, reducing Levodopa's premature breakdown. This allows more Levodopa to enter the brain and be converted into dopamine, leading to improved symptom control. As a result, patients often experience a reduction in tremors, rigidity, and slowness of movement.
Benefits of the Medication
Many patients report significant improvements in their daily functioning after starting Carbidopa / Levodopa. The medication provides relief from disabling motor symptoms and enhances quality of life. It is particularly effective in the early to middle stages of Parkinson's disease. The combination also tends to have a quick onset of action, with some patients noticing symptom relief within a short period after taking the medication. Over time, the medication can help manage fluctuations in symptoms and reduce the severity of Parkinsonian tremors and stiffness.
Potential Side Effects
Like all medications, Carbidopa / Levodopa can cause side effects. Common issues include nausea, dizziness, and orthostatic hypotension, which is a sudden drop in blood pressure when standing up. Some patients may experience involuntary movements, such as twitching or jerking, especially with long-term use. Sleep disturbances, confusion, or hallucinations can also occur, particularly in older adults. It is important to monitor for these side effects and communicate with a healthcare provider to adjust the dosage or explore alternative therapies if needed.
Precautions and Interactions
Patients should inform their healthcare provider about any other medications they are taking, as Carbidopa / Levodopa can interact with various drugs, including certain antidepressants, antipsychotics, and blood pressure medications. People with certain medical conditions, such as glaucoma or a history of melanoma, should use this medication with caution. Regular blood pressure monitoring is recommended to detect any significant changes. Additionally, sudden cessation of the medication can lead to a neuroleptic malignant syndrome or worsening symptoms, so discontinuation should always be gradual under medical supervision.
Usage and Dosage
The exact dosage varies depending on individual needs and response. Typically, the medication is taken multiple times a day, with or without food, as prescribed by a healthcare professional. Consistency in timing and adherence to the prescribed dosage are crucial for optimal results. Patients should follow their doctor's instructions carefully and avoid altering the dose without consultation. Regular follow-up appointments are essential to assess effectiveness and manage side effects.
Conclusion
Carbidopa / Levodopa remains a cornerstone in the treatment of Parkinson's disease. Its ability to effectively control motor symptoms and improve quality of life has made it invaluable for many patients. While side effects and interactions are possible, they can often be managed with proper medical oversight. When used appropriately, this medication offers significant benefits for those living with Parkinson’s, enabling better mobility and independence.