Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 2,5mg | ||||
360 pill | 2,5mg | NZD312.54 | NZD0.87 | |
180 pill | 2,5mg | NZD168.15 | NZD0.93 | |
120 pill | 2,5mg | NZD120.59 | NZD1.00 | |
90 pill | 2,5mg | NZD98.51 | NZD1.09 | |
60 pill | 2,5mg | NZD71.33 | NZD1.19 | |
30 pill | 2,5mg | NZD42.45 | NZD1.41 | |
Dosage: 5mg | ||||
360 pill | 5mg | NZD275.17 | NZD0.76 | |
180 pill | 5mg | NZD159.66 | NZD0.88 | |
120 pill | 5mg | NZD112.10 | NZD0.93 | |
90 pill | 5mg | NZD88.31 | NZD0.99 | |
60 pill | 5mg | NZD61.14 | NZD1.02 | |
30 pill | 5mg | NZD35.66 | NZD1.19 |
Glibenclamide Description
Introduction to Glibenclamide
Glibenclamide, also known as Glyburide in some regions, is a commonly prescribed medication used primarily to manage type 2 diabetes. It belongs to the class of drugs called sulfonylureas, which work by stimulating the release of insulin from the pancreatic beta cells. This action helps to lower blood sugar levels and improve glycemic control in diabetic patients. The medication is often prescribed as part of a comprehensive treatment plan that includes diet, exercise, and other lifestyle modifications.
How Glibenclamide Works
Glibenclamide acts by binding to specific receptors on pancreatic cells. This binding closes potassium channels, leading to cell depolarization. As a result, calcium channels open, allowing calcium ions into the cells. The influx of calcium stimulates the secretion of insulin. By increasing insulin levels, Glibenclamide helps to reduce high blood sugar levels, thereby decreasing the risk of complications associated with uncontrolled diabetes, such as nerve damage, kidney problems, and cardiovascular issues.
Effectiveness and Usage
Many patients find Glibenclamide effective in maintaining appropriate blood glucose levels when taken as prescribed. It is usually administered orally, once or twice daily, depending on individual needs and physician recommendations. For optimal results, it is essential for patients to adhere strictly to the prescribed dosage and schedule. Regular monitoring of blood sugar levels helps ensure that the medication is working effectively and helps adjust the dosage if needed. Combining Glibenclamide with a balanced diet and physical activity enhances its effectiveness and supports overall health management.
Possible Side Effects
Like any medication, Glibenclamide can cause side effects. The most common include hypoglycemia (low blood sugar), which can present as sweating, dizziness, weakness, and hunger. Patients should be aware of these signs and know how to respond appropriately. Some individuals may experience gastrointestinal issues such as nausea, diarrhea, or stomach discomfort. Allergic reactions, though rare, can occur and may include rash, itching, or swelling. It is crucial for patients to report any unusual or severe side effects to their healthcare provider promptly. Proper dosage adjustment and monitoring can help minimize adverse reactions.
Precautions and Contraindications
Glibenclamide should be used cautiously in certain populations, including pregnant or breastfeeding women, and individuals with kidney or liver impairment. It is contraindicated in patients with allergies to sulfonylureas or other components of the medication. Furthermore, since it can cause hypoglycemia, patients with conditions that predispose them to low blood sugar levels should be monitored closely. It is essential to inform healthcare providers about all medications being taken, as Glibenclamide can interact with other drugs, such as beta-blockers, antibiotics, and certain antifungals, which may affect its efficacy or increase side effects.
Conclusion
Glibenclamide remains a valuable option for managing type 2 diabetes in many patients. Its ability to effectively lower blood sugar levels can help prevent complications associated with the disease. However, it requires proper use, frequent monitoring, and awareness of potential side effects. Patients should work closely with their healthcare providers to ensure that they use the medication safely and effectively, ensuring the best possible outcome for their health.