Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 10mg | ||||
360 pill | 10mg | NZD312.54 | NZD0.87 | |
270 pill | 10mg | NZD254.78 | NZD0.95 | |
180 pill | 10mg | NZD183.44 | NZD1.02 | |
120 pill | 10mg | NZD154.56 | NZD1.29 | |
90 pill | 10mg | NZD130.78 | NZD1.46 | |
60 pill | 10mg | NZD113.79 | NZD1.90 | |
30 pill | 10mg | NZD59.44 | NZD1.99 | |
20 pill | 10mg | NZD42.45 | NZD2.12 | |
Dosage: 20mg | ||||
270 pill | 20mg | NZD305.74 | NZD1.14 | |
180 pill | 20mg | NZD232.70 | NZD1.29 | |
120 pill | 20mg | NZD174.95 | NZD1.46 | |
90 pill | 20mg | NZD144.37 | NZD1.60 | |
60 pill | 20mg | NZD113.79 | NZD1.90 | |
30 pill | 20mg | NZD66.23 | NZD2.21 | |
20 pill | 20mg | NZD49.24 | NZD2.46 |

Tamoxifen Description
Overview of Tamoxifen
Tamoxifen is a widely used medication primarily known for its role in treating breast cancer. It belongs to a class of drugs called selective estrogen receptor modulators (SERMs). By blocking estrogen receptors in breast tissue, Tamoxifen helps prevent the growth and spread of hormone receptor-positive breast cancer cells. It is often prescribed for both early-stage and advanced breast cancer, as well as for reducing the risk of developing breast cancer in high-risk individuals.
Mechanism of Action
The effectiveness of Tamoxifen lies in its ability to interfere with estrogen’s action. Estrogen can promote the growth of certain types of breast cancer. Tamoxifen binds to estrogen receptors on cancer cells, preventing estrogen from attaching. This inhibition slows down or halts the growth of estrogen-dependent tumors. The drug acts differently in various tissues: in breast tissue, it acts as an antagonist, while in bones and the endometrium, it may have partial agonist effects. This dual action contributes to its therapeutic benefits and associated risks.
Therapeutic Uses
Designed mainly for breast cancer management, Tamoxifen is used in several treatment settings. It helps in adjuvant therapy after surgery to eliminate residual cancer cells. In metastatic breast cancer, it can help in controlling tumor growth and alleviating symptoms. Additionally, Tamoxifen is prescribed as a preventive measure for women at high risk of developing breast cancer. It has also shown potential in reducing the risk of recurrence in patients who have already undergone primary treatment.
Potential Benefits
The benefits of Tamoxifen include its ability to significantly reduce breast cancer recurrence rates and improve survival outcomes. For high-risk women, it offers a preventive strategy, decreasing the likelihood of developing cancer. Some patients also experience bone health benefits because of its estrogen-like effects on bones, which can help maintain bone density. Overall, Tamoxifen has played a critical role in the breast cancer treatment landscape, offering hope and improved prognosis for many patients.
Possible Side Effects and Risks
While Tamoxifen is effective, it is associated with certain side effects that patients should be aware of. Common issues include hot flashes, night sweats, and nausea. Some women may experience changes in menstrual cycles or vaginal discharge. Importantly, Tamoxifen can increase the risk of blood clots, which may lead to deep vein thrombosis or pulmonary embolism. There is also a slight increased risk of endometrial cancer, which necessitates regular monitoring. Long-term use requires careful evaluation by healthcare professionals to balance benefits and risks.
Precautions and Considerations
Before starting Tamoxifen, patients should disclose their full medical history, especially related to blood clots, uterine health, and liver function. Women who are pregnant or breastfeeding should not use this medication. Regular follow-up appointments are essential to monitor for any adverse effects and to evaluate the ongoing need for therapy. Patients should report any unusual symptoms such as abnormal vaginal bleeding, severe headaches, or leg pain promptly. Combining Tamoxifen with other medications should always be managed by a healthcare provider to prevent interactions.
Conclusion
In summary, Tamoxifen remains a cornerstone in the treatment and prevention of estrogen receptor-positive breast cancer. Its ability to inhibit tumor growth has significantly improved outcomes for many patients. However, like all medications, it requires careful management to mitigate potential side effects. Patients considering Tamoxifen should consult their healthcare providers to understand its benefits and risks fully. Proper monitoring and adherence to prescribed regimens can help maximize its therapeutic potential while minimizing adverse effects.