Antidepressants

Antidepressants are medications commonly prescribed to treat depression and other mood disorders. They help balance chemicals in the brain that affect mood and emotions. This category includes several types of drugs, each working in unique ways. Here is a review of some popular antidepressants available in the market.

Abilify is an atypical antipsychotic also used as an add-on treatment for depression. It helps improve mood when traditional antidepressants alone are insufficient. Patients often report fewer side effects compared to older drugs.

Bupropion SR (Sustained Release) is known for its stimulating effects. It is useful for patients dealing with fatigue and low energy. Unlike many antidepressants, it does not usually cause weight gain or sexual dysfunction. It is also prescribed to aid smoking cessation.

Celexa (Citalopram) belongs to the SSRI class. It increases serotonin levels in the brain, improving mood and anxiety symptoms. It has a relatively mild side effect profile, although some users experience nausea or insomnia.

Cymbalta (Duloxetine) is an SNRI that affects serotonin and norepinephrine. It is effective not only for depression but also for nerve pain and anxiety disorders. Side effects may include dry mouth, dizziness, and tiredness.

Desyrel (Trazodone) is often prescribed for depression and insomnia. It has a sedative effect, making it a good choice for patients with sleep issues. However, some patients may experience dizziness or headaches.

Effexor and Effexor XR (Venlafaxine and its extended-release version) are SNRIs. They help balance serotonin and norepinephrine and are effective for major depression, anxiety, and panic disorders. Common side effects include increased blood pressure and nausea.

Elavil (Amitriptyline) is a tricyclic antidepressant. It is effective for depression and neuropathic pain. Due to its side effect profile, including dry mouth and drowsiness, it is generally not the first choice.

Endep is another brand of amitriptyline with similar uses and side effects as Elavil. It offers relief for mood disorders and chronic pain conditions.

Eskalith (Lithium) is primarily a mood stabilizer but also helps prevent depressive episodes in bipolar disorder. Regular monitoring of blood levels is necessary due to potential toxicity.

Geodon (Ziprasidone) is an atypical antipsychotic used as an adjunct for depression with psychotic features or bipolar disorder. It is known for a lower risk of weight gain but may cause restlessness or sedation.

Lexapro (Escitalopram) is a well-tolerated SSRI often prescribed for depression and anxiety. It is praised for its quick onset and fewer side effects compared to older SSRIs.

Luvox (Fluvoxamine) is effective for depression and obsessive-compulsive disorder. Some patients report gastrointestinal issues and sleep disturbances.

Nortriptyline is a tricyclic antidepressant similar to amitriptyline but with a somewhat better side effect profile. It is used for depression and nerve pain.

Pamelor (Nortriptyline) is another commonly prescribed tricyclic. It can cause dry mouth, blurred vision, and drowsiness but works well for resistant depression.

Paxil and Paxil CR (Paroxetine and its controlled release form) are SSRIs effective for depression, anxiety disorders, and PTSD. However, they may cause sexual dysfunction and weight gain.

Remeron (Mirtazapine) is known for its sedative effects. It increases appetite and helps patients with insomnia and weight loss related to depression. Daytime drowsiness is a common complaint.

Risnia, Risperdal, Seroquel, Zyprexa are atypical antipsychotics sometimes used off-label for depression, especially when accompanied by psychotic symptoms or bipolar disorder. They can cause weight gain and metabolic changes.

Sinequan (Doxepin) is a tricyclic with strong sedative properties and is often used for anxiety and sleep disturbances associated with depression. Side effects include dry mouth and dizziness.

Tofranil (Imipramine) is one of the oldest tricyclics. It is effective but has considerable side effects like heart palpitations and fatigue.

Venlor (Venlafaxine) is similar to Effexor and helps with depression and anxiety. Some users experience increased blood pressure and sweating.

Wellbutrin and Wellbutrin SR (Bupropion and its sustained-release version) stand out for not causing sexual side effects. They are stimulating and support quitting smoking. Anxiety may worsen in some patients initially.

Each antidepressant has unique benefits and drawbacks. Choice depends on symptoms, side effects, and medical history. Patients should always follow medical advice and report any adverse effects promptly. Monitoring and adjusting treatment ensures the best outcomes in managing depression.